Michiko to Hatchin follows the journey of two very different individuals across a vibrant South American-inspired landscape. Michiko, a hardened criminal, escapes prison with a specific goal: to find someone from her past.
She unexpectedly crosses paths with Hana, a young girl trapped in an abusive situation. Michiko claims to be Hana's mother, rescuing her and pulling her into a life on the run.
Together, they navigate a dangerous world filled with poverty, exploitation, and betrayal, all while pursuing Michiko's mysterious objective. Their journey will test their bond as they are pursued by both law enforcement and powerful criminal organizations drawn into their path.
The anime explores the complex relationships and motivations of the characters they encounter, highlighting the unlikely connections formed amidst chaos and uncertainty. The central mystery revolves around the person Michiko is searching for, and the consequences of that search for both her and Hatchin.