Kodaka Hasegawa, transferring to a new school, hopes to finally make friends but is immediately ostracized due to his appearance.
Finding himself alone, he encounters Yozora Mikazuki, another loner who talks to an imaginary friend.
Together, they decide to form the Neighbor's Club, a group dedicated to helping its members learn social skills and make friends.
As other quirky and friendless students join the club, Kodaka finds himself surrounded by an unlikely group of companions, each with their own unique personalities and challenges in navigating social interactions.
The anime follows the Neighbor's Club members as they try to overcome their social awkwardness and learn what it truly means to be friends.